ATP8A1

ATPase phospholipid transporting 8A1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

GO terms:

Biological Process:
lipid transport [GO:0006869],
learning [GO:0007612],
positive regulation of cell migration [GO:0030335],
ion transmembrane transport [GO:0034220],
neutrophil degranulation [GO:0043312],
phospholipid translocation [GO:0045332],
transmembrane transport [GO:0055085],
positive regulation of phospholipid translocation [GO:0061092],
cation transmembrane transport [GO:0098655],
phospholipid transport [GO:0015914],

Molecular Function:
magnesium ion binding [GO:0000287],
protein binding [GO:0005515],
ATP binding [GO:0005524],
ATPase activity [GO:0016887],
cation-transporting ATPase activity [GO:0019829],
transmembrane transporter activity [GO:0022857],
nucleotide binding [GO:0000166],
metal ion binding [GO:0046872],

Cellular Component:
endoplasmic reticulum [GO:0005783],
Golgi apparatus [GO:0005794],
trans-Golgi network [GO:0005802],
plasma membrane [GO:0005886],
membrane [GO:0016020],
integral component of synaptic vesicle membrane [GO:0030285],
azurophil granule membrane [GO:0035577],
specific granule membrane [GO:0035579],
chromaffin granule membrane [GO:0042584],
intracellular membrane-bounded organelle [GO:0043231],
extracellular exosome [GO:0070062],
integral component of membrane [GO:0016021],
cytoplasmic vesicle [GO:0031410],