PLXNB1

plexin B1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
negative regulation of cell adhesion [GO:0007162],
signal transduction [GO:0007165],
G-protein coupled receptor signaling pathway [GO:0007186],
regulation of cell shape [GO:0008360],
positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068],
cell migration [GO:0016477],
regulation of cell migration [GO:0030334],
negative regulation of osteoblast proliferation [GO:0033689],
intracellular signal transduction [GO:0035556],
regulation of GTPase activity [GO:0043087],
positive regulation of GTPase activity [GO:0043547],
ossification involved in bone maturation [GO:0043931],
neuron projection morphogenesis [GO:0048812],
positive regulation of axonogenesis [GO:0050772],
regulation of cytoskeleton organization [GO:0051493],
semaphorin-plexin signaling pathway [GO:0071526],
semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [GO:1900220],
semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287],
inhibitory synapse assembly [GO:1904862],

Molecular Function:
transmembrane signaling receptor activity [GO:0004888],
GTPase activator activity [GO:0005096],
protein binding [GO:0005515],
semaphorin receptor activity [GO:0017154],
semaphorin receptor binding [GO:0030215],
GTPase activating protein binding [GO:0032794],
signaling receptor activity [GO:0038023],

Cellular Component:
semaphorin receptor complex [GO:0002116],
extracellular region [GO:0005576],
plasma membrane [GO:0005886],
integral component of plasma membrane [GO:0005887],
membrane [GO:0016020],
integral component of membrane [GO:0016021],