PLSCR3

phospholipid scramblase 3

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Li Fraumeni Human YES

GO terms:

Biological Process:
apoptotic process [GO:0006915],
phospholipid scrambling [GO:0017121],
glucose homeostasis [GO:0042593],
cholesterol homeostasis [GO:0042632],
cellular response to lipopolysaccharide [GO:0071222],

Molecular Function:
calcium ion binding [GO:0005509],
protein binding [GO:0005515],
SH3 domain binding [GO:0017124],
phospholipid scramblase activity [GO:0017128],
calcium-dependent protein binding [GO:0048306],

Cellular Component:
mitochondrion [GO:0005739],
plasma membrane [GO:0005886],
integral component of membrane [GO:0016021],
mitochondrial membrane [GO:0031966],
membrane [GO:0016020],