ATPase H+ transporting V1 subunit H

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA57 Skin, Lung Human YES
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945125 Primary astrocytes derived from brain Human YES
32029712 Primary synovial fibroblast Human YES

GO terms:

Biological Process:
endocytosis [GO:0006897],
vacuolar acidification [GO:0007035],
insulin receptor signaling pathway [GO:0008286],
regulation of macroautophagy [GO:0016241],
transferrin transport [GO:0033572],
ion transmembrane transport [GO:0034220],
regulation of defense response to virus by virus [GO:0050690],
regulation of catalytic activity [GO:0050790],
phagosome acidification [GO:0090383],
hydrogen ion transmembrane transport [GO:1902600],
ion transport [GO:0006811],

Molecular Function:
protein binding [GO:0005515],
ATPase activity [GO:0016887],
enzyme regulator activity [GO:0030234],
proton-transporting ATPase activity, rotational mechanism [GO:0046961],

Cellular Component:
vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221],
lysosomal membrane [GO:0005765],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
extracellular exosome [GO:0070062],