PLEC

plectin

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
30987592 MCF7 Breast Human YES
31945054 IMR-90, primary epithelial cells derived from kidney Human YES

GO terms:

Biological Process:
hemidesmosome assembly [GO:0031581],
wound healing [GO:0042060],
intermediate filament cytoskeleton organization [GO:0045104],
response to nutrient [GO:0007584],

Molecular Function:
RNA binding [GO:0003723],
actin binding [GO:0003779],
structural molecule activity [GO:0005198],
structural constituent of cytoskeleton [GO:0005200],
protein binding [GO:0005515],
structural constituent of muscle [GO:0008307],
ankyrin binding [GO:0030506],
cadherin binding [GO:0045296],
cytoskeletal protein binding [GO:0008092],
protein N-terminus binding [GO:0047485],

Cellular Component:
cytoplasm [GO:0005737],
cytosol [GO:0005829],
intermediate filament [GO:0005882],
plasma membrane [GO:0005886],
brush border [GO:0005903],
focal adhesion [GO:0005925],
membrane [GO:0016020],
sarcoplasm [GO:0016528],
hemidesmosome [GO:0030056],
sarcolemma [GO:0042383],
costamere [GO:0043034],
intermediate filament cytoskeleton [GO:0045111],
perinuclear region of cytoplasm [GO:0048471],
extracellular exosome [GO:0070062],
cytoskeleton [GO:0005856],
basal plasma membrane [GO:0009925],
apical plasma membrane [GO:0016324],
cell junction [GO:0030054],
contractile fiber [GO:0043292],