ATPase H+ transporting V1 subunit A

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
cellular iron ion homeostasis [GO:0006879],
insulin receptor signaling pathway [GO:0008286],
regulation of macroautophagy [GO:0016241],
transferrin transport [GO:0033572],
ion transmembrane transport [GO:0034220],
cellular response to increased oxygen levels [GO:0036295],
ATP metabolic process [GO:0046034],
phagosome acidification [GO:0090383],
hydrogen ion transmembrane transport [GO:1902600],
ion transport [GO:0006811],

Molecular Function:
ATP binding [GO:0005524],
proton-transporting ATPase activity, rotational mechanism [GO:0046961],
nucleotide binding [GO:0000166],

Cellular Component:
lysosomal membrane [GO:0005765],
vacuolar membrane [GO:0005774],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
microvillus [GO:0005902],
apical plasma membrane [GO:0016324],
proton-transporting two-sector ATPase complex [GO:0016469],
proton-transporting V-type ATPase, V1 domain [GO:0033180],
extracellular exosome [GO:0070062],
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],
myelin sheath [GO:0043209],