phosphatidylinositol-5-phosphate 4-kinase type 2 alpha

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
phospholipid metabolic process [GO:0006644],
phosphatidylinositol biosynthetic process [GO:0006661],
regulation of autophagy [GO:0010506],
regulation of phosphatidylinositol 3-kinase signaling [GO:0014066],
megakaryocyte development [GO:0035855],
phosphatidylinositol phosphorylation [GO:0046854],
positive regulation of autophagosome assembly [GO:2000786],
phosphorylation [GO:0016310],
phosphatidylinositol metabolic process [GO:0046488],

Molecular Function:
ATP binding [GO:0005524],
1-phosphatidylinositol-4-phosphate 5-kinase activity [GO:0016308],
1-phosphatidylinositol-5-phosphate 4-kinase activity [GO:0016309],
nucleotide binding [GO:0000166],
protein binding [GO:0005515],
kinase activity [GO:0016301],
phosphatidylinositol phosphate kinase activity [GO:0016307],
transferase activity [GO:0016740],

Cellular Component:
nucleoplasm [GO:0005654],
autophagosome [GO:0005776],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
nucleus [GO:0005634],
cytoplasm [GO:0005737],
membrane [GO:0016020],