ATP6V0C

ATPase H+ transporting V0 subunit c

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Li Fraumeni Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
insulin receptor signaling pathway [GO:0008286],
viral process [GO:0016032],
regulation of macroautophagy [GO:0016241],
positive regulation of Wnt signaling pathway [GO:0030177],
transferrin transport [GO:0033572],
ion transmembrane transport [GO:0034220],
neutrophil degranulation [GO:0043312],
phagosome acidification [GO:0090383],
hydrogen ion transmembrane transport [GO:1902600],
ion transport [GO:0006811],
vacuolar acidification [GO:0007035],
lysosomal lumen acidification [GO:0007042],
positive regulation of ERK1 and ERK2 cascade [GO:0070374],
negative regulation of autophagic cell death [GO:1904093],

Molecular Function:
protein binding [GO:0005515],
ubiquitin protein ligase binding [GO:0031625],
proton-transporting ATP synthase activity, rotational mechanism [GO:0046933],
proton-transporting ATPase activity, rotational mechanism [GO:0046961],
hydrogen-exporting ATPase activity, phosphorylative mechanism [GO:0008553],
hydrogen ion transmembrane transporter activity [GO:0015078],

Cellular Component:
lysosomal membrane [GO:0005765],
plasma membrane [GO:0005886],
focal adhesion [GO:0005925],
endosome membrane [GO:0010008],
integral component of membrane [GO:0016021],
phagocytic vesicle membrane [GO:0030670],
proton-transporting V-type ATPase, V0 domain [GO:0033179],
azurophil granule membrane [GO:0035577],
extracellular exosome [GO:0070062],
tertiary granule membrane [GO:0070821],
ficolin-1-rich granule membrane [GO:0101003],
lysosome [GO:0005764],
vacuole [GO:0005773],
Golgi apparatus [GO:0005794],
synaptic vesicle [GO:0008021],
membrane [GO:0016020],
vacuolar proton-transporting V-type ATPase complex [GO:0016471],
proton-transporting two-sector ATPase complex, proton-transporting domain [GO:0033177],