ATPase H+ transporting V0 subunit a4

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES
30987592 MCF7 Breast Human YES
30988157 IMR-90 Human YES

GO terms:

Biological Process:
ossification [GO:0001503],
regulation of pH [GO:0006885],
vacuolar acidification [GO:0007035],
excretion [GO:0007588],
sensory perception of sound [GO:0007605],
insulin receptor signaling pathway [GO:0008286],
transferrin transport [GO:0033572],
ion transmembrane transport [GO:0034220],
phagosome acidification [GO:0090383],
hydrogen ion transmembrane transport [GO:1902600],
ion transport [GO:0006811],

Molecular Function:
protein binding [GO:0005515],
proton-transporting ATPase activity, rotational mechanism [GO:0046961],
ATPase binding [GO:0051117],
hydrogen-exporting ATPase activity, phosphorylative mechanism [GO:0008553],
hydrogen ion transmembrane transporter activity [GO:0015078],

Cellular Component:
vacuolar proton-transporting V-type ATPase, V0 domain [GO:0000220],
lysosomal membrane [GO:0005765],
endosome [GO:0005768],
plasma membrane [GO:0005886],
endosome membrane [GO:0010008],
integral component of membrane [GO:0016021],
apical plasma membrane [GO:0016324],
vacuolar proton-transporting V-type ATPase complex [GO:0016471],
phagocytic vesicle membrane [GO:0030670],
brush border membrane [GO:0031526],
apical part of cell [GO:0045177],
extracellular exosome [GO:0070062],
brush border [GO:0005903],
membrane [GO:0016020],
proton-transporting V-type ATPase, V0 domain [GO:0033179],