ATPase H+ transporting V0 subunit a1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945125 Primary astrocytes derived from brain Human YES
32029712 Primary synovial fibroblast Human YES

GO terms:

Biological Process:
vacuolar acidification [GO:0007035],
insulin receptor signaling pathway [GO:0008286],
regulation of macroautophagy [GO:0016241],
transferrin transport [GO:0033572],
ion transmembrane transport [GO:0034220],
neutrophil degranulation [GO:0043312],
phagosome acidification [GO:0090383],
toxin transport [GO:1901998],
hydrogen ion transmembrane transport [GO:1902600],
ion transport [GO:0006811],

Molecular Function:
protein binding [GO:0005515],
proton-transporting ATPase activity, rotational mechanism [GO:0046961],
ATPase binding [GO:0051117],
hydrogen ion transmembrane transporter activity [GO:0015078],

Cellular Component:
vacuolar proton-transporting V-type ATPase, V0 domain [GO:0000220],
lysosomal membrane [GO:0005765],
Golgi apparatus [GO:0005794],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
endosome membrane [GO:0010008],
integral component of membrane [GO:0016021],
vacuolar proton-transporting V-type ATPase complex [GO:0016471],
nuclear speck [GO:0016607],
secretory granule membrane [GO:0030667],
phagocytic vesicle membrane [GO:0030670],
melanosome [GO:0042470],
intracellular membrane-bounded organelle [GO:0043231],
perinuclear region of cytoplasm [GO:0048471],
extracellular exosome [GO:0070062],
ficolin-1-rich granule membrane [GO:0101003],
cytoplasm [GO:0005737],
synaptic vesicle [GO:0008021],
membrane [GO:0016020],
integral component of synaptic vesicle membrane [GO:0030285],
cytoplasmic vesicle [GO:0031410],
proton-transporting V-type ATPase, V0 domain [GO:0033179],
intracellular organelle [GO:0043229],