PGF

placental growth factor

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
30988157 IMR-90 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Li Fraumeni Human YES
32029712 Primary synovial fibroblast Human YES

GO terms:

Biological Process:
angiogenesis [GO:0001525],
branching involved in ureteric bud morphogenesis [GO:0001658],
response to hypoxia [GO:0001666],
positive regulation of protein phosphorylation [GO:0001934],
positive regulation of endothelial cell proliferation [GO:0001938],
sprouting angiogenesis [GO:0002040],
signal transduction [GO:0007165],
cell-cell signaling [GO:0007267],
female pregnancy [GO:0007565],
positive regulation of cell proliferation [GO:0008284],
cell differentiation [GO:0030154],
animal organ regeneration [GO:0031100],
cellular response to hormone stimulus [GO:0032870],
vascular endothelial growth factor signaling pathway [GO:0038084],
response to drug [GO:0042493],
positive regulation of angiogenesis [GO:0045766],
vascular endothelial growth factor receptor signaling pathway [GO:0048010],
positive chemotaxis [GO:0050918],
induction of positive chemotaxis [GO:0050930],
positive regulation of cell division [GO:0051781],
regulation of morphogenesis of a branching structure [GO:0060688],
positive regulation of mast cell chemotaxis [GO:0060754],
multicellular organism development [GO:0007275],

Molecular Function:
vascular endothelial growth factor receptor binding [GO:0005172],
protein binding [GO:0005515],
growth factor activity [GO:0008083],
heparin binding [GO:0008201],
chemoattractant activity [GO:0042056],
identical protein binding [GO:0042802],
macromolecular complex binding [GO:0044877],

Cellular Component:
extracellular region [GO:0005576],
extracellular space [GO:0005615],
membrane [GO:0016020],