PGAM5

PGAM family member 5, mitochondrial serine/threonine protein phosphatase

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
programmed cell death [GO:0012501],
necroptotic process [GO:0070266],
protein dephosphorylation [GO:0006470],
macroautophagy [GO:0016236],
positive regulation of GTPase activity [GO:0043547],

Molecular Function:
phosphoprotein phosphatase activity [GO:0004721],
protein serine/threonine phosphatase activity [GO:0004722],
GTPase activator activity [GO:0005096],
hydrolase activity [GO:0016787],
phosphatase activity [GO:0016791],
macromolecular complex binding [GO:0044877],
protein binding [GO:0005515],

Cellular Component:
mitochondrion [GO:0005739],
mitochondrial outer membrane [GO:0005741],
membrane [GO:0016020],
integral component of membrane [GO:0016021],