PEPD

peptidase D

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31148378 MRC-5 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 Skin, Lung Human YES

GO terms:

Biological Process:
proteolysis [GO:0006508],
cellular amino acid metabolic process [GO:0006520],
collagen catabolic process [GO:0030574],

Molecular Function:
aminopeptidase activity [GO:0004177],
metallocarboxypeptidase activity [GO:0004181],
protein binding [GO:0005515],
peptidase activity [GO:0008233],
manganese ion binding [GO:0030145],
proline dipeptidase activity [GO:0102009],
metallopeptidase activity [GO:0008237],
hydrolase activity [GO:0016787],
dipeptidase activity [GO:0016805],
metal ion binding [GO:0046872],

Cellular Component:
extracellular exosome [GO:0070062],