ATP2C2
ATPase secretory pathway Ca2+ transporting 2
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
Pubmed ID | Cell line | Tissue | Source | High-throughput |
29548335 | Li Fraumeni | Human | YES |
GO terms:
Biological Process:
manganese ion transport [GO:0006828],
cellular calcium ion homeostasis [GO:0006874],
ion transmembrane transport [GO:0034220],
mammary gland epithelium development [GO:0061180],
calcium ion transmembrane transport [GO:0070588],
manganese ion transmembrane transport [GO:0071421],
protein localization to plasma membrane [GO:0072659],
positive regulation of calcium ion import [GO:0090280],
hydrogen ion transmembrane transport [GO:1902600],
ion transport [GO:0006811],
calcium ion transport [GO:0006816],
Molecular Function:
calcium-transporting ATPase activity [GO:0005388],
protein binding [GO:0005515],
ATP binding [GO:0005524],
hydrogen-exporting ATPase activity, phosphorylative mechanism [GO:0008553],
manganese-transporting ATPase activity [GO:0015410],
ATPase activity [GO:0016887],
metal ion binding [GO:0046872],
nucleotide binding [GO:0000166],
Cellular Component:
Golgi membrane [GO:0000139],
endoplasmic reticulum [GO:0005783],
plasma membrane [GO:0005886],
cytoplasmic side of plasma membrane [GO:0009898],
integral component of membrane [GO:0016021],
cytoplasmic vesicle [GO:0031410],
perinuclear region of cytoplasm [GO:0048471],
membrane [GO:0016020],