ATPase secretory pathway Ca2+ transporting 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA642 Skin, Lung Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
calcium ion transport [GO:0006816],
manganese ion transport [GO:0006828],
cellular calcium ion homeostasis [GO:0006874],
epidermis development [GO:0008544],
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339],
actin cytoskeleton reorganization [GO:0031532],
Golgi calcium ion homeostasis [GO:0032468],
Golgi calcium ion transport [GO:0032472],
ion transmembrane transport [GO:0034220],
positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123],
calcium ion transmembrane transport [GO:0070588],
manganese ion transmembrane transport [GO:0071421],
hydrogen ion transmembrane transport [GO:1902600],
ion transport [GO:0006811],
cellular manganese ion homeostasis [GO:0030026],

Molecular Function:
calcium-transporting ATPase activity [GO:0005388],
ATP binding [GO:0005524],
hydrogen-exporting ATPase activity, phosphorylative mechanism [GO:0008553],
manganese-transporting ATPase activity [GO:0015410],
ATPase activity [GO:0016887],
metal ion binding [GO:0046872],
nucleotide binding [GO:0000166],
calcium ion binding [GO:0005509],
manganese ion binding [GO:0030145],

Cellular Component:
Golgi membrane [GO:0000139],
endoplasmic reticulum [GO:0005783],
Golgi apparatus [GO:0005794],
trans-Golgi network [GO:0005802],
plasma membrane [GO:0005886],
membrane [GO:0016020],
integral component of membrane [GO:0016021],
transport vesicle [GO:0030133],
secretory granule [GO:0030141],
intracellular membrane-bounded organelle [GO:0043231],