PDLIM3

PDZ and LIM domain 3

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
32972203 heartDPI14 vs healthy Endothelial cell Mouse NO

GO terms:

Biological Process:
actin filament organization [GO:0007015],
heart development [GO:0007507],
actin cytoskeleton organization [GO:0030036],
muscle structure development [GO:0061061],
skeletal muscle tissue development [GO:0007519],

Molecular Function:
actin binding [GO:0003779],
protein binding [GO:0005515],
structural constituent of muscle [GO:0008307],
metal ion binding [GO:0046872],
muscle alpha-actinin binding [GO:0051371],
cytoskeletal protein binding [GO:0008092],

Cellular Component:
stress fiber [GO:0001725],
cytosol [GO:0005829],
adherens junction [GO:0005912],
Z disc [GO:0030018],
filamentous actin [GO:0031941],
cytoplasm [GO:0005737],
actin cytoskeleton [GO:0015629],