ATP1B3

ATPase Na+/K+ transporting subunit beta 3

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 Skin, Lung Human YES
31983656 MSC Human YES

GO terms:

Biological Process:
cellular sodium ion homeostasis [GO:0006883],
establishment or maintenance of transmembrane electrochemical gradient [GO:0010248],
cellular potassium ion homeostasis [GO:0030007],
positive regulation of ATPase activity [GO:0032781],
ion transmembrane transport [GO:0034220],
sodium ion transmembrane transport [GO:0035725],
sodium ion export from cell [GO:0036376],
protein stabilization [GO:0050821],
leukocyte migration [GO:0050900],
potassium ion transmembrane transport [GO:0071805],
protein localization to plasma membrane [GO:0072659],
membrane repolarization [GO:0086009],
positive regulation of potassium ion transmembrane transporter activity [GO:1901018],
positive regulation of sodium ion export from cell [GO:1903278],
positive regulation of potassium ion import [GO:1903288],
regulation of cardiac conduction [GO:1903779],
potassium ion import across plasma membrane [GO:1990573],
ion transport [GO:0006811],
potassium ion transport [GO:0006813],
sodium ion transport [GO:0006814],
metal ion transport [GO:0030001],

Molecular Function:
ATPase activator activity [GO:0001671],
sodium:potassium-exchanging ATPase activity [GO:0005391],
cation-transporting ATPase activity [GO:0019829],
ATPase binding [GO:0051117],
protein binding [GO:0005515],

Cellular Component:
plasma membrane [GO:0005886],
sodium:potassium-exchanging ATPase complex [GO:0005890],
caveola [GO:0005901],
sperm flagellum [GO:0036126],
melanosome [GO:0042470],
extracellular exosome [GO:0070062],
cytoplasm [GO:0005737],
membrane [GO:0016020],
integral component of membrane [GO:0016021],