PARPBP

PARP1 binding protein

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
27323328 Saos-2,H1299, HT18, MCF7, MDA-MB-231, Li-Fraumeni Human YES
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Saos-2 Human YES
30988157 IMR-90 Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
DNA repair [GO:0006281],
negative regulation of double-strand break repair via homologous recombination [GO:2000042],
cellular response to DNA damage stimulus [GO:0006974],

Molecular Function:
DNA binding [GO:0003677],
protein binding [GO:0005515],
molecular_function [GO:0003674],

Cellular Component:
chromatin [GO:0000785],
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
nucleus [GO:0005634],