PAPPA2

pappalysin 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
proteolysis [GO:0006508],
bone morphogenesis [GO:0060349],
regulation of cell growth [GO:0001558],
response to salt stress [GO:0009651],
cellular protein metabolic process [GO:0044267],

Molecular Function:
metalloendopeptidase activity [GO:0004222],
metallopeptidase activity [GO:0008237],
zinc ion binding [GO:0008270],

Cellular Component:
cytosol [GO:0005829],
apical plasma membrane [GO:0016324],
extracellular region [GO:0005576],
extracellular exosome [GO:0070062],