ATOX1

antioxidant 1 copper chaperone

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 Skin, Lung Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
copper ion transport [GO:0006825],
cellular copper ion homeostasis [GO:0006878],
response to oxidative stress [GO:0006979],
negative regulation of apoptotic process [GO:0043066],
copper ion export [GO:0060003],
ion transport [GO:0006811],
metal ion transport [GO:0030001],

Molecular Function:
copper ion binding [GO:0005507],
protein binding [GO:0005515],
metallochaperone activity [GO:0016530],
copper chaperone activity [GO:0016531],
copper-dependent protein binding [GO:0032767],
ATPase binding [GO:0051117],
metal ion binding [GO:0046872],

Cellular Component:
cytosol [GO:0005829],