PAFAH1B1

platelet activating factor acetylhydrolase 1b regulatory subunit 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

GO terms:

Biological Process:
G2/M transition of mitotic cell cycle [GO:0000086],
establishment of mitotic spindle orientation [GO:0000132],
microtubule cytoskeleton organization [GO:0000226],
ameboidal-type cell migration [GO:0001667],
acrosome assembly [GO:0001675],
neuron migration [GO:0001764],
positive regulation of cytokine-mediated signaling pathway [GO:0001961],
microtubule-based process [GO:0007017],
nuclear migration [GO:0007097],
chemical synaptic transmission [GO:0007268],
germ cell development [GO:0007281],
neuroblast proliferation [GO:0007405],
learning or memory [GO:0007611],
retrograde axonal transport [GO:0008090],
adult locomotory behavior [GO:0008344],
protein secretion [GO:0009306],
regulation of G2/M transition of mitotic cell cycle [GO:0010389],
negative regulation of neuron projection development [GO:0010977],
lipid catabolic process [GO:0016042],
stem cell division [GO:0017145],
transmission of nerve impulse [GO:0019226],
corpus callosum morphogenesis [GO:0021540],
hippocampus development [GO:0021766],
layer formation in cerebral cortex [GO:0021819],
cerebral cortex neuron differentiation [GO:0021895],
cerebral cortex development [GO:0021987],
actin cytoskeleton organization [GO:0030036],
microtubule organizing center organization [GO:0031023],
osteoclast development [GO:0036035],
positive regulation of embryonic development [GO:0040019],
establishment of planar polarity of embryonic epithelium [GO:0042249],
regulation of GTPase activity [GO:0043087],
cortical microtubule organization [GO:0043622],
positive regulation of axon extension [GO:0045773],
positive regulation of mitotic cell cycle [GO:0045931],
negative regulation of JNK cascade [GO:0046329],
platelet activating factor metabolic process [GO:0046469],
vesicle transport along microtubule [GO:0047496],
brain morphogenesis [GO:0048854],
neuromuscular process controlling balance [GO:0050885],
microtubule sliding [GO:0051012],
nuclear envelope disassembly [GO:0051081],
establishment of centrosome localization [GO:0051660],
maintenance of centrosome location [GO:0051661],
auditory receptor cell development [GO:0060117],
positive regulation of dendritic spine morphogenesis [GO:0061003],
regulation of microtubule cytoskeleton organization [GO:0070507],
cochlea development [GO:0090102],
microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176],
ciliary basal body docking [GO:0097711],
regulation of microtubule motor activity [GO:2000574],
lipid metabolic process [GO:0006629],
cell cycle [GO:0007049],
multicellular organism development [GO:0007275],
nervous system development [GO:0007399],
cell migration [GO:0016477],
cell differentiation [GO:0030154],
positive regulation of cellular component organization [GO:0051130],
cell division [GO:0051301],

Molecular Function:
protein binding [GO:0005515],
microtubule binding [GO:0008017],
heparin binding [GO:0008201],
dynactin binding [GO:0034452],
identical protein binding [GO:0042802],
phospholipase binding [GO:0043274],
dynein intermediate chain binding [GO:0045505],
microtubule plus-end binding [GO:0051010],
phosphoprotein binding [GO:0051219],
dynein complex binding [GO:0070840],
macromolecular complex binding [GO:0044877],

Cellular Component:
astral microtubule [GO:0000235],
kinetochore [GO:0000776],
nuclear envelope [GO:0005635],
centrosome [GO:0005813],
cytosol [GO:0005829],
kinesin complex [GO:0005871],
microtubule associated complex [GO:0005875],
cytoplasmic microtubule [GO:0005881],
cell cortex [GO:0005938],
cell leading edge [GO:0031252],
motile cilium [GO:0031514],
nuclear membrane [GO:0031965],
stereocilium [GO:0032420],
neuron projection [GO:0043005],
neuronal cell body [GO:0043025],
synapse [GO:0045202],
perinuclear region of cytoplasm [GO:0048471],
extracellular exosome [GO:0070062],
axon cytoplasm [GO:1904115],
nucleus [GO:0005634],
cytoplasm [GO:0005737],
cytoskeleton [GO:0005856],
microtubule [GO:0005874],
microtubule cytoskeleton [GO:0015630],
membrane [GO:0016020],
axon [GO:0030424],
growth cone [GO:0030426],
vesicle [GO:0031982],
non-motile cilium [GO:0097730],