PACSIN3

protein kinase C and casein kinase substrate in neurons 3

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
30987592 MCF7 Breast Human YES

GO terms:

Biological Process:
endocytosis [GO:0006897],
cytoskeleton organization [GO:0007010],
regulation of endocytosis [GO:0030100],
negative regulation of endocytosis [GO:0045806],
positive regulation of membrane protein ectodomain proteolysis [GO:0051044],
negative regulation of calcium ion transport [GO:0051926],
membrane tubulation [GO:0097320],

Molecular Function:
protein binding [GO:0005515],
phospholipid binding [GO:0005543],
cytoskeletal protein binding [GO:0008092],
lipid binding [GO:0008289],
calcium channel inhibitor activity [GO:0019855],

Cellular Component:
cytoplasm [GO:0005737],
endosome [GO:0005768],
cytosol [GO:0005829],
cytoskeleton [GO:0005856],
plasma membrane [GO:0005886],
extracellular exosome [GO:0070062],
trans-Golgi network [GO:0005802],
membrane [GO:0016020],