OMA1 zinc metallopeptidase

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

GO terms:

Biological Process:
diet induced thermogenesis [GO:0002024],
glucose metabolic process [GO:0006006],
proteolysis [GO:0006508],
misfolded or incompletely synthesized protein catabolic process [GO:0006515],
lipid metabolic process [GO:0006629],
mitochondrion organization [GO:0007005],
negative regulation of mitochondrial fusion [GO:0010637],
mitochondrial protein processing [GO:0034982],
cristae formation [GO:0042407],
energy homeostasis [GO:0097009],
regulation of apoptotic process [GO:0042981],

Molecular Function:
metalloendopeptidase activity [GO:0004222],
peptidase activity [GO:0008233],
metallopeptidase activity [GO:0008237],
hydrolase activity [GO:0016787],
metal ion binding [GO:0046872],

Cellular Component:
mitochondrion [GO:0005739],
mitochondrial inner membrane [GO:0005743],
membrane [GO:0016020],
integral component of membrane [GO:0016021],
mitochondrial membrane [GO:0031966],