autophagy related 4B cysteine peptidase

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
21678067 C85 Human NO
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA696 Skin, Lung Human YES

GO terms:

Biological Process:
proteolysis [GO:0006508],
autophagy [GO:0006914],
protein transport [GO:0015031],
macroautophagy [GO:0016236],
positive regulation of protein catabolic process [GO:0045732],
protein delipidation [GO:0051697],
autophagosome assembly [GO:0000045],
cellular response to starvation [GO:0009267],

Molecular Function:
endopeptidase activity [GO:0004175],
cysteine-type endopeptidase activity [GO:0004197],
protein binding [GO:0005515],
cysteine-type peptidase activity [GO:0008234],
peptidase activity [GO:0008233],
hydrolase activity [GO:0016787],

Cellular Component:
cytosol [GO:0005829],
cytoplasm [GO:0005737],