autophagy related 3

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
30894058 RAW 264.7 Mouse NO
32972203 heartDPI14 vs healthy nan Mouse NO

GO terms:

Biological Process:
autophagosome assembly [GO:0000045],
mitophagy [GO:0000422],
cellular protein modification process [GO:0006464],
protein targeting to membrane [GO:0006612],
macroautophagy [GO:0016236],
protein ubiquitination [GO:0016567],
mitochondrial fragmentation involved in apoptotic process [GO:0043653],
nucleophagy [GO:0044804],
negative regulation of phagocytosis [GO:0050765],
regulation of cilium assembly [GO:1902017],
autophagy [GO:0006914],
protein transport [GO:0015031],

Molecular Function:
protein binding [GO:0005515],
Atg8 ligase activity [GO:0019776],
Atg12 transferase activity [GO:0019777],
ubiquitin-like protein transferase activity [GO:0019787],
enzyme binding [GO:0019899],
transferase activity [GO:0016740],

Cellular Component:
cytoplasmic ubiquitin ligase complex [GO:0000153],
cytosol [GO:0005829],
cytoplasm [GO:0005737],