NRP2

neuropilin 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
30977188 MSC Human YES
31945125 Primary astrocytes derived from brain Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
33296652 heart heart Human NO

GO terms:

Biological Process:
angiogenesis [GO:0001525],
positive regulation of endothelial cell proliferation [GO:0001938],
outflow tract septum morphogenesis [GO:0003148],
cell adhesion [GO:0007155],
axon guidance [GO:0007411],
positive regulation of endothelial cell migration [GO:0010595],
viral process [GO:0016032],
facial nerve structural organization [GO:0021612],
vestibulocochlear nerve structural organization [GO:0021649],
nerve development [GO:0021675],
gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828],
ventral trunk neural crest cell migration [GO:0036486],
vascular endothelial growth factor signaling pathway [GO:0038084],
vascular endothelial growth factor receptor signaling pathway [GO:0048010],
axon extension involved in axon guidance [GO:0048846],
negative chemotaxis [GO:0050919],
sympathetic ganglion development [GO:0061549],
trigeminal ganglion development [GO:0061551],
sensory neuron axon guidance [GO:0097374],
sympathetic neuron projection extension [GO:0097490],
sympathetic neuron projection guidance [GO:0097491],
neural crest cell migration involved in autonomic nervous system development [GO:1901166],
semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285],
facioacoustic ganglion development [GO:1903375],
dorsal root ganglion morphogenesis [GO:1904835],
cellular response to leukemia inhibitory factor [GO:1990830],
neural crest cell migration [GO:0001755],
neuron migration [GO:0001764],
multicellular organism development [GO:0007275],
nervous system development [GO:0007399],
heart development [GO:0007507],
cell differentiation [GO:0030154],

Molecular Function:
vascular endothelial growth factor-activated receptor activity [GO:0005021],
protein binding [GO:0005515],
heparin binding [GO:0008201],
semaphorin receptor activity [GO:0017154],
growth factor binding [GO:0019838],
cytokine binding [GO:0019955],
signaling receptor activity [GO:0038023],
metal ion binding [GO:0046872],
identical protein binding [GO:0042802],

Cellular Component:
semaphorin receptor complex [GO:0002116],
extracellular region [GO:0005576],
plasma membrane [GO:0005886],
membrane [GO:0016020],
integral component of membrane [GO:0016021],
axon [GO:0030424],
glutamatergic synapse [GO:0098978],
integral component of postsynaptic membrane [GO:0099055],