ATG14

autophagy related 14

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
autophagosome assembly [GO:0000045],
macromitophagy [GO:0000423],
regulation of protein phosphorylation [GO:0001932],
negative regulation of protein phosphorylation [GO:0001933],
positive regulation of protein phosphorylation [GO:0001934],
endosome to lysosome transport [GO:0008333],
cellular response to starvation [GO:0009267],
posttranscriptional regulation of gene expression [GO:0010608],
macroautophagy [GO:0016236],
autophagosome docking [GO:0016240],
cellular response to glucose starvation [GO:0042149],
positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552],
regulation of protein complex stability [GO:0061635],
regulation of triglyceride metabolic process [GO:0090207],
response to mitochondrial depolarisation [GO:0098780],
autophagy [GO:0006914],

Molecular Function:
protein binding [GO:0005515],
GTPase binding [GO:0051020],

Cellular Component:
autophagosome membrane [GO:0000421],
autophagosome [GO:0005776],
endoplasmic reticulum membrane [GO:0005789],
cytosol [GO:0005829],
axoneme [GO:0005930],
pre-autophagosomal structure membrane [GO:0034045],
phosphatidylinositol 3-kinase complex, class III [GO:0035032],
ER-mitochondrion membrane contact site [GO:0044233],
phagocytic vesicle [GO:0045335],
extrinsic component of omegasome membrane [GO:0097629],
extrinsic component of pre-autophagosomal structure membrane [GO:0097632],
cytoplasm [GO:0005737],
endoplasmic reticulum [GO:0005783],
membrane [GO:0016020],
cytoplasmic vesicle [GO:0031410],