ATG13

autophagy related 13

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31983656 MSC Human YES

GO terms:

Biological Process:
autophagosome assembly [GO:0000045],
mitophagy [GO:0000422],
macromitophagy [GO:0000423],
macroautophagy [GO:0016236],
regulation of macroautophagy [GO:0016241],
activation of protein kinase activity [GO:0032147],
protein localization to pre-autophagosomal structure [GO:0034497],
piecemeal microautophagy of nucleus [GO:0034727],
nucleophagy [GO:0044804],
response to mitochondrial depolarisation [GO:0098780],
positive regulation of protein targeting to mitochondrion [GO:1903955],
autophagy [GO:0006914],

Molecular Function:
protein binding [GO:0005515],
protein kinase regulator activity [GO:0019887],
protein kinase binding [GO:0019901],

Cellular Component:
pre-autophagosomal structure [GO:0000407],
mitochondrion [GO:0005739],
endoplasmic reticulum membrane [GO:0005789],
cytosol [GO:0005829],
extrinsic component of membrane [GO:0019898],
ATG1/ULK1 kinase complex [GO:1990316],
cytoplasm [GO:0005737],