ATG12

autophagy related 12

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
21678067 C85 Human NO

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
21858089 HDF Human NO

GO terms:

Biological Process:
autophagosome assembly [GO:0000045],
mitophagy [GO:0000422],
C-terminal protein lipidation [GO:0006501],
viral process [GO:0016032],
macroautophagy [GO:0016236],
nucleophagy [GO:0044804],
autophagy [GO:0006914],

Molecular Function:
protein binding [GO:0005515],
Atg8 ligase activity [GO:0019776],

Cellular Component:
autophagosome [GO:0005776],
cytosol [GO:0005829],
phagocytic vesicle membrane [GO:0030670],
pre-autophagosomal structure membrane [GO:0034045],
Atg12-Atg5-Atg16 complex [GO:0034274],
cytoplasm [GO:0005737],
membrane [GO:0016020],
macromolecular complex [GO:0032991],