ATF6B

activating transcription factor 6 beta

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

GO terms:

Biological Process:
transcription, DNA-templated [GO:0006351],
signal transduction [GO:0007165],
ATF6-mediated unfolded protein response [GO:0036500],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
negative regulation of ATF6-mediated unfolded protein response [GO:1903892],
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440],
regulation of transcription, DNA-templated [GO:0006355],
regulation of transcription from RNA polymerase II promoter [GO:0006357],
response to unfolded protein [GO:0006986],
endoplasmic reticulum unfolded protein response [GO:0030968],

Molecular Function:
transcription regulatory region sequence-specific DNA binding [GO:0000976],
RNA polymerase II core promoter proximal region sequence-specific DNA binding [GO:0000978],
RNA polymerase II transcription factor activity, sequence-specific DNA binding [GO:0000981],
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding [GO:0001228],
transcription factor activity, sequence-specific DNA binding [GO:0003700],
protein binding [GO:0005515],
cAMP response element binding [GO:0035497],
DNA binding [GO:0003677],

Cellular Component:
nuclear chromatin [GO:0000790],
nucleus [GO:0005634],
endoplasmic reticulum membrane [GO:0005789],
Golgi apparatus [GO:0005794],
integral component of endoplasmic reticulum membrane [GO:0030176],
protein-DNA complex [GO:0032993],
RNA polymerase II transcription factor complex [GO:0090575],
intracellular [GO:0005622],
endoplasmic reticulum [GO:0005783],
endomembrane system [GO:0012505],
membrane [GO:0016020],
integral component of membrane [GO:0016021],