Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
27140416 MRC-5 , WI-38, BJ, IMR-90 Human NO
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
regulation of gluconeogenesis [GO:0006111],
proteolysis [GO:0006508],
peptide metabolic process [GO:0006518],
regulation of skeletal muscle fiber differentiation [GO:1902809],

Molecular Function:
metalloendopeptidase activity [GO:0004222],
peptide binding [GO:0042277],
metal ion binding [GO:0046872],
peptidase activity [GO:0008233],
metallopeptidase activity [GO:0008237],
hydrolase activity [GO:0016787],
oligopeptidase activity [GO:0070012],

Cellular Component:
extracellular region [GO:0005576],
mitochondrial intermembrane space [GO:0005758],
plasma membrane [GO:0005886],
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],
cytosol [GO:0005829],