ATPase family AAA domain containing 2B

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA556 Skin, Lung Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
negative regulation of chromatin silencing [GO:0031936],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],

Molecular Function:
chromatin binding [GO:0003682],
ATP binding [GO:0005524],
ATPase activity [GO:0016887],
histone binding [GO:0042393],
lysine-acetylated histone binding [GO:0070577],

Cellular Component:
nucleus [GO:0005634],
nucleoplasm [GO:0005654],