ATAD2
ATPase family AAA domain containing 2
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 23691139 | Huh7, Hnheps, HepG2, Hep3B, Hep4, PLC/PRF/5, SNU-387, SNU- 398, SNU-423, SNU-449, SNU-475, FOCUS, Mahlavu, SK- Hep-1, FLC4 | Liver | Human | NO |
| 30987592 | MCF7 | Breast | Human | YES |
| 31945125 | Primary astrocytes derived from brain | Human | YES | |
GO terms:
Biological Process:
chromatin organization [GO:0006325],
regulation of transcription from RNA polymerase II promoter [GO:0006357],
negative regulation of chromatin silencing [GO:0031936],
positive regulation of transcription, DNA-templated [GO:0045893],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
regulation of transcription, DNA-templated [GO:0006355],
Molecular Function:
chromatin binding [GO:0003682],
protein binding [GO:0005515],
ATP binding [GO:0005524],
ATPase activity [GO:0016887],
histone binding [GO:0042393],
nucleotide binding [GO:0000166],
hydrolase activity [GO:0016787],
Cellular Component:
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
extracellular exosome [GO:0070062],