ATPase family AAA domain containing 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31148378 MRC-5 Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
positive regulation of receptor internalization [GO:0002092],
learning [GO:0007612],
memory [GO:0007613],
negative regulation of synaptic transmission, glutamatergic [GO:0051967],

Molecular Function:
nucleotide binding [GO:0000166],
protein binding [GO:0005515],
ATP binding [GO:0005524],
hydrolase activity [GO:0016787],
ATPase activity [GO:0016887],

Cellular Component:
mitochondrion [GO:0005739],
peroxisome [GO:0005777],
plasma membrane [GO:0005886],
membrane [GO:0016020],
cell junction [GO:0030054],
synapse [GO:0045202],
postsynaptic membrane [GO:0045211],
postsynapse [GO:0098794],
glutamatergic synapse [GO:0098978],
peroxisomal membrane [GO:0005778],