ASXL2
ASXL transcriptional regulator 2
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Down-regulated | ||||
Pubmed ID | Cell line | Tissue | Source | High-throughput |
29548335 | Li Fraumeni | Human | YES |
GO terms:
Biological Process:
transcription, DNA-templated [GO:0006351],
animal organ morphogenesis [GO:0009887],
positive regulation of lipid storage [GO:0010884],
protein deubiquitination [GO:0016579],
positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360],
positive regulation of fat cell differentiation [GO:0045600],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
negative regulation of transcription from RNA polymerase II promoter [GO:0000122],
heart morphogenesis [GO:0003007],
regulation of transcription, DNA-templated [GO:0006355],
heart development [GO:0007507],
adult heart development [GO:0007512],
positive regulation of osteoclast differentiation [GO:0045672],
embryonic skeletal system morphogenesis [GO:0048704],
positive regulation of bone mineralization involved in bone maturation [GO:1900159],
positive regulation of histone H3-K27 trimethylation [GO:1902466],
Molecular Function:
DNA binding [GO:0003677],
chromatin binding [GO:0003682],
peroxisome proliferator activated receptor binding [GO:0042975],
metal ion binding [GO:0046872],
Cellular Component:
nuclear chromatin [GO:0000790],
nucleoplasm [GO:0005654],
PR-DUB complex [GO:0035517],
nucleus [GO:0005634],