asparaginase and isoaspartyl peptidase 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
asparagine catabolic process via L-aspartate [GO:0033345],
proteolysis [GO:0006508],
L-phenylalanine catabolic process [GO:0006559],

Molecular Function:
asparaginase activity [GO:0004067],
peptidase activity [GO:0008233],
beta-aspartyl-peptidase activity [GO:0008798],
hydrolase activity [GO:0016787],
N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity [GO:0003948],

Cellular Component:
photoreceptor inner segment [GO:0001917],
cytoplasm [GO:0005737],
nucleus [GO:0005634],
cytosol [GO:0005829],