ACAA1

acetyl-CoA acyltransferase 1

Link to human ortholog


Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
very long-chain fatty acid metabolic process [GO:0000038],
protein targeting to peroxisome [GO:0006625],
fatty acid beta-oxidation [GO:0006635],
bile acid metabolic process [GO:0008206],
phenylacetate catabolic process [GO:0010124],
fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540],
alpha-linolenic acid metabolic process [GO:0036109],
neutrophil degranulation [GO:0043312],

Molecular Function:
acetyl-CoA C-acyltransferase activity [GO:0003988],
protein binding [GO:0005515],
acetate CoA-transferase activity [GO:0008775],
palmitoyl-CoA oxidase activity [GO:0016401],
acetyl-CoA C-myristoyltransferase activity [GO:0050633],

Cellular Component:
extracellular region [GO:0005576],
peroxisome [GO:0005777],
peroxisomal matrix [GO:0005782],
cytosol [GO:0005829],
membrane [GO:0016020],
specific granule lumen [GO:0035580],
intracellular membrane-bounded organelle [GO:0043231],