acid sensing ion channel subunit 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2, Li-Fraumeni Human YES

GO terms:

Biological Process:
regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback [GO:0003026],
chemical synaptic transmission [GO:0007268],
central nervous system development [GO:0007417],
peripheral nervous system development [GO:0007422],
phototransduction [GO:0007602],
sensory perception of sound [GO:0007605],
response to acidic pH [GO:0010447],
monovalent inorganic cation transport [GO:0015672],
regulation of vasoconstriction [GO:0019229],
ion transmembrane transport [GO:0034220],
regulation of ion transmembrane transport [GO:0034765],
protein localization to synapse [GO:0035418],
sodium ion transmembrane transport [GO:0035725],
regulation of membrane potential [GO:0042391],
negative regulation of apoptotic process [GO:0043066],
sensory perception of sour taste [GO:0050915],
detection of mechanical stimulus involved in sensory perception [GO:0050974],
positive regulation of synapse assembly [GO:0051965],
ion transport [GO:0006811],
cation transport [GO:0006812],
sodium ion transport [GO:0006814],
response to mechanical stimulus [GO:0009612],
cellular response to drug [GO:0035690],
cellular response to acidic pH [GO:0071468],
positive regulation of cation channel activity [GO:2001259],

Molecular Function:
protein binding [GO:0005515],
ligand-gated sodium channel activity [GO:0015280],
ion gated channel activity [GO:0022839],
ion channel activity [GO:0005216],
voltage-gated sodium channel activity [GO:0005248],
cation channel activity [GO:0005261],
sodium channel activity [GO:0005272],

Cellular Component:
plasma membrane [GO:0005886],
integral component of plasma membrane [GO:0005887],
neuronal cell body [GO:0043025],
dendritic spine [GO:0043197],
membrane [GO:0016020],
integral component of membrane [GO:0016021],
neuron projection [GO:0043005],
synapse [GO:0045202],