N-acetylated alpha-linked acidic dipeptidase 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA83 Skin, Lung Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
proteolysis [GO:0006508],
cellular amino acid biosynthetic process [GO:0008652],
neurotransmitter catabolic process [GO:0042135],
metabolic process [GO:0008152],

Molecular Function:
carboxypeptidase activity [GO:0004180],
serine-type peptidase activity [GO:0008236],
metallopeptidase activity [GO:0008237],
dipeptidyl-peptidase activity [GO:0008239],
dipeptidase activity [GO:0016805],
metal ion binding [GO:0046872],
N-formylglutamate deformylase activity [GO:0050129],
catalytic activity [GO:0003824],
peptidase activity [GO:0008233],
hydrolase activity [GO:0016787],

Cellular Component:
plasma membrane [GO:0005886],
integral component of membrane [GO:0016021],
membrane [GO:0016020],