ASF1B
anti-silencing function 1B histone chaperone
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 27323328 | Saos-2,H1299, HT18, MCF7, MDA-MB-231, Li-Fraumeni | Human | YES | |
| 29548335 | Saos-2 | Human | YES | |
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 29321003 | Primary bronchial epithelial cells derived from lung | Human | YES | |
| 30987592 | MCF7 | Breast | Human | YES |
| 30988157 | IMR-90 | Human | YES | |
| 31945125 | Primary astrocytes derived from brain | Human | YES | |
GO terms:
Biological Process:
blastocyst hatching [GO:0001835],
DNA replication-dependent nucleosome assembly [GO:0006335],
DNA replication-independent nucleosome assembly [GO:0006336],
spermatogenesis [GO:0007283],
cell differentiation [GO:0030154],
chromatin organization [GO:0006325],
chromatin assembly or disassembly [GO:0006333],
nucleosome assembly [GO:0006334],
Molecular Function:
protein binding [GO:0005515],
histone binding [GO:0042393],
Cellular Component:
nuclear chromatin [GO:0000790],
nucleoplasm [GO:0005654],
macromolecular complex [GO:0032991],
chromatin [GO:0000785],
nucleus [GO:0005634],