ASF1B

anti-silencing function 1B histone chaperone

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
27323328 Saos-2,H1299, HT18, MCF7, MDA-MB-231, Li-Fraumeni Human YES
29548335 Saos-2 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
30987592 MCF7 Breast Human YES
30988157 IMR-90 Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
blastocyst hatching [GO:0001835],
DNA replication-dependent nucleosome assembly [GO:0006335],
DNA replication-independent nucleosome assembly [GO:0006336],
spermatogenesis [GO:0007283],
cell differentiation [GO:0030154],
chromatin organization [GO:0006325],
chromatin assembly or disassembly [GO:0006333],
nucleosome assembly [GO:0006334],

Molecular Function:
protein binding [GO:0005515],
histone binding [GO:0042393],

Cellular Component:
nuclear chromatin [GO:0000790],
nucleoplasm [GO:0005654],
macromolecular complex [GO:0032991],
chromatin [GO:0000785],
nucleus [GO:0005634],