ASF1A
anti-silencing function 1A histone chaperone
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 31742863 | Yeast | NO | ||
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 30692519 | HepG2, LNCaP, AGS, MCF-7, HCT-116, UMSC | Liver | Human | NO |
| 31945125 | Primary astrocytes derived from brain | Human | YES | |
GO terms:
Biological Process:
osteoblast differentiation [GO:0001649],
DNA repair [GO:0006281],
nucleosome assembly [GO:0006334],
DNA replication-dependent nucleosome assembly [GO:0006335],
DNA replication-independent nucleosome assembly [GO:0006336],
negative regulation of chromatin silencing [GO:0031936],
muscle cell differentiation [GO:0042692],
chromatin organization [GO:0006325],
chromatin assembly or disassembly [GO:0006333],
Molecular Function:
chromatin binding [GO:0003682],
protein binding [GO:0005515],
histone binding [GO:0042393],
Cellular Component:
nuclear chromatin [GO:0000790],
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
macromolecular complex [GO:0032991],