anti-silencing function 1A histone chaperone

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31742863 Yeast NO

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
30692519 HepG2, LNCaP, AGS, MCF-7, HCT-116, UMSC Liver Human NO
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
osteoblast differentiation [GO:0001649],
DNA repair [GO:0006281],
nucleosome assembly [GO:0006334],
DNA replication-dependent nucleosome assembly [GO:0006335],
DNA replication-independent nucleosome assembly [GO:0006336],
negative regulation of chromatin silencing [GO:0031936],
muscle cell differentiation [GO:0042692],
chromatin organization [GO:0006325],
chromatin assembly or disassembly [GO:0006333],

Molecular Function:
chromatin binding [GO:0003682],
protein binding [GO:0005515],
histone binding [GO:0042393],

Cellular Component:
nuclear chromatin [GO:0000790],
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
macromolecular complex [GO:0032991],