MYOD1

myogenic differentiation 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31962055 IMR-90, primary fibroblasts derived from lung Lung Human, mouse NO

GO terms:

Biological Process:
regulation of alternative mRNA splicing, via spliceosome [GO:0000381],
regulation of transcription from RNA polymerase II promoter [GO:0006357],
protein phosphorylation [GO:0006468],
muscle organ development [GO:0007517],
myoblast fate determination [GO:0007518],
skeletal muscle tissue development [GO:0007519],
myoblast fusion [GO:0007520],
cellular response to starvation [GO:0009267],
myotube cell development [GO:0014904],
myotube differentiation involved in skeletal muscle regeneration [GO:0014908],
skeletal muscle cell differentiation [GO:0035914],
muscle cell fate commitment [GO:0042693],
positive regulation of skeletal muscle tissue regeneration [GO:0043415],
regulation of RNA splicing [GO:0043484],
skeletal muscle fiber adaptation [GO:0043503],
histone H3 acetylation [GO:0043966],
histone H4 acetylation [GO:0043967],
positive regulation of myoblast differentiation [GO:0045663],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
skeletal muscle fiber development [GO:0048741],
positive regulation of skeletal muscle fiber development [GO:0048743],
positive regulation of muscle cell differentiation [GO:0051149],
cellular response to tumor necrosis factor [GO:0071356],
cellular response to glucocorticoid stimulus [GO:0071385],
cellular response to estradiol stimulus [GO:0071392],
cellular response to oxygen levels [GO:0071453],
positive regulation of myoblast fusion [GO:1901741],
positive regulation of snRNA transcription from RNA polymerase II promoter [GO:1905382],
negative regulation of myoblast proliferation [GO:2000818],
regulation of transcription, DNA-templated [GO:0006355],
multicellular organism development [GO:0007275],
regulation of gene expression [GO:0010468],
myotube differentiation [GO:0014902],
cell differentiation [GO:0030154],
negative regulation of chromatin binding [GO:0035562],
skeletal muscle tissue regeneration [GO:0043403],
myoblast differentiation [GO:0045445],
positive regulation of transcription, DNA-templated [GO:0045893],
positive regulation of binding [GO:0051099],
striated muscle cell differentiation [GO:0051146],
cardiac muscle cell differentiation [GO:0055007],

Molecular Function:
RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977],
RNA polymerase II core promoter proximal region sequence-specific DNA binding [GO:0000978],
RNA polymerase II transcription factor activity, sequence-specific DNA binding [GO:0000981],
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding [GO:0001228],
chromatin binding [GO:0003682],
transcription coactivator activity [GO:0003713],
protein binding [GO:0005515],
chromatin DNA binding [GO:0031490],
ubiquitin protein ligase binding [GO:0031625],
nuclear hormone receptor binding [GO:0035257],
protein dimerization activity [GO:0046983],
E-box binding [GO:0070888],
promoter-specific chromatin binding [GO:1990841],
core promoter proximal region sequence-specific DNA binding [GO:0000987],
DNA binding [GO:0003677],
transcription factor activity, sequence-specific DNA binding [GO:0003700],
transcription factor binding [GO:0008134],
enzyme binding [GO:0019899],
sequence-specific DNA binding [GO:0043565],

Cellular Component:
nuclear chromatin [GO:0000790],
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
transcription factor complex [GO:0005667],
myofibril [GO:0030016],
cytoplasm [GO:0005737],