ASCC3

activating signal cointegrator 1 complex subunit 3

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
DNA dealkylation involved in DNA repair [GO:0006307],
cell proliferation [GO:0008283],
DNA duplex unwinding [GO:0032508],
DNA repair [GO:0006281],
cellular response to DNA damage stimulus [GO:0006974],

Molecular Function:
RNA binding [GO:0003723],
protein binding [GO:0005515],
ATP binding [GO:0005524],
3'-5' DNA helicase activity [GO:0043138],
nucleotide binding [GO:0000166],
nucleic acid binding [GO:0003676],
helicase activity [GO:0004386],
hydrolase activity [GO:0016787],

Cellular Component:
intracellular [GO:0005622],
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
cytosol [GO:0005829],
membrane [GO:0016020],
nuclear speck [GO:0016607],
activating signal cointegrator 1 complex [GO:0099053],