ASB2
ankyrin repeat and SOCS box containing 2
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 30988157 | IMR-90 | Human | YES | |
| 31945054 | IMR-90 | Human | YES | |
| 31945125 | Primary astrocytes derived from brain | Human | YES | |
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 33296652 | heart | heart | Human | NO |
GO terms:
Biological Process:
ubiquitin-dependent protein catabolic process [GO:0006511],
signal transduction [GO:0007165],
protein ubiquitination [GO:0016567],
intracellular signal transduction [GO:0035556],
skeletal muscle cell differentiation [GO:0035914],
post-translational protein modification [GO:0043687],
protein polyubiquitination [GO:0000209],
myoblast differentiation [GO:0045445],
Molecular Function:
protein binding [GO:0005515],
ubiquitin protein ligase activity [GO:0061630],
Cellular Component:
ubiquitin ligase complex [GO:0000151],
cytosol [GO:0005829],
Cul5-RING ubiquitin ligase complex [GO:0031466],