ankyrin repeat and SOCS box containing 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
protein ubiquitination [GO:0016567],
male genitalia development [GO:0030539],
intracellular signal transduction [GO:0035556],
negative regulation of cytokine biosynthetic process [GO:0042036],
post-translational protein modification [GO:0043687],
multicellular organism development [GO:0007275],

Molecular Function:
protein binding [GO:0005515],
ubiquitin protein ligase activity [GO:0061630],

Cellular Component:
ubiquitin ligase complex [GO:0000151],
cytosol [GO:0005829],