ArfGAP with SH3 domain, ankyrin repeat and PH domain 3

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
cell migration [GO:0016477],
positive regulation of GTPase activity [GO:0043547],
regulation of stress fiber assembly [GO:0051492],

Molecular Function:
GTPase activator activity [GO:0005096],
protein binding [GO:0005515],
metal ion binding [GO:0046872],

Cellular Component:
ruffle [GO:0001726],
nucleoplasm [GO:0005654],
cytosol [GO:0005829],
focal adhesion [GO:0005925],
intracellular membrane-bounded organelle [GO:0043231],
cytoplasm [GO:0005737],