Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
19555429 Primary endothelial cells derived from human Human NO
20376899 Primary endothelial cells derived from human Human NO

GO terms:

Biological Process:
immunological synapse formation [GO:0001771],
cytoskeleton organization [GO:0007010],
leukocyte cell-cell adhesion [GO:0007159],
regulation of cell shape [GO:0008360],
regulation of cell size [GO:0008361],
positive regulation of gene expression [GO:0010628],
viral process [GO:0016032],
gland morphogenesis [GO:0022612],
membrane to membrane docking [GO:0022614],
interleukin-12-mediated signaling pathway [GO:0035722],
T cell proliferation [GO:0042098],
establishment of epithelial cell apical/basal polarity [GO:0045198],
leukocyte migration [GO:0050900],
establishment of endothelial barrier [GO:0061028],
T cell aggregation [GO:0070489],
cellular response to testosterone stimulus [GO:0071394],
positive regulation of podosome assembly [GO:0071803],
T cell migration [GO:0072678],
regulation of organelle assembly [GO:1902115],
positive regulation of protein localization to early endosome [GO:1902966],
positive regulation of cellular protein catabolic process [GO:1903364],
regulation of lymphocyte migration [GO:2000401],
positive regulation of early endosome to late endosome transport [GO:2000643],

Molecular Function:
double-stranded RNA binding [GO:0003725],
actin binding [GO:0003779],
receptor binding [GO:0005102],
structural constituent of cytoskeleton [GO:0005200],
protein binding [GO:0005515],
enzyme binding [GO:0019899],
protein kinase binding [GO:0019901],
cell adhesion molecule binding [GO:0050839],
cytoskeletal protein binding [GO:0008092],

Cellular Component:
uropod [GO:0001931],
extracellular space [GO:0005615],
nucleus [GO:0005634],
cytoplasm [GO:0005737],
cytosol [GO:0005829],
cytoskeleton [GO:0005856],
plasma membrane [GO:0005886],
microvillus [GO:0005902],
focal adhesion [GO:0005925],
cell surface [GO:0009986],
basolateral plasma membrane [GO:0016323],
apical plasma membrane [GO:0016324],
filopodium [GO:0030175],
pseudopodium [GO:0031143],
microvillus membrane [GO:0031528],
vesicle [GO:0031982],
apical part of cell [GO:0045177],
perinuclear region of cytoplasm [GO:0048471],
extracellular exosome [GO:0070062],
invadopodium [GO:0071437],
cell periphery [GO:0071944],
blood microparticle [GO:0072562],
cytoplasmic side of plasma membrane [GO:0009898],
membrane [GO:0016020],
T-tubule [GO:0030315],
secretory granule membrane [GO:0030667],
filopodium membrane [GO:0031527],
cell projection [GO:0042995],
myelin sheath [GO:0043209],
cell tip [GO:0051286],