arylsulfatase A

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
glycosphingolipid metabolic process [GO:0006687],
neutrophil degranulation [GO:0043312],
autophagy [GO:0006914],
binding of sperm to zona pellucida [GO:0007339],
central nervous system development [GO:0007417],
response to nutrient [GO:0007584],
response to pH [GO:0009268],
response to estrogen [GO:0043627],
response to ethanol [GO:0045471],
response to methylmercury [GO:0051597],

Molecular Function:
arylsulfatase activity [GO:0004065],
cerebroside-sulfatase activity [GO:0004098],
calcium ion binding [GO:0005509],
protein binding [GO:0005515],
sulfuric ester hydrolase activity [GO:0008484],
catalytic activity [GO:0003824],
hydrolase activity [GO:0016787],
metal ion binding [GO:0046872],

Cellular Component:
extracellular region [GO:0005576],
lysosome [GO:0005764],
endoplasmic reticulum lumen [GO:0005788],
azurophil granule lumen [GO:0035578],
lysosomal lumen [GO:0043202],
extracellular exosome [GO:0070062],
acrosomal vesicle [GO:0001669],
extracellular space [GO:0005615],
cytoplasm [GO:0005737],
endosome [GO:0005768],
endoplasmic reticulum [GO:0005783],
plasma membrane [GO:0005886],
integral component of membrane [GO:0016021],
extrinsic component of external side of plasma membrane [GO:0031232],