ARRDC4

arrestin domain containing 4

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31615473 WI-38, IMR-90, HUVEC, HAEC Human YES
31945054 IMR-90 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
ubiquitin-dependent protein catabolic process [GO:0006511],
protein transport [GO:0015031],
protein ubiquitination [GO:0016567],
positive regulation of ubiquitin-protein transferase activity [GO:0051443],

Molecular Function:
protein binding, bridging involved in substrate recognition for ubiquitination [GO:1990756],
protein binding [GO:0005515],

Cellular Component:
cytoplasm [GO:0005737],
endosome [GO:0005768],
plasma membrane [GO:0005886],
membrane [GO:0016020],
cytoplasmic vesicle [GO:0031410],
intracellular membrane-bounded organelle [GO:0043231],
extracellular vesicle [GO:1903561],
early endosome [GO:0005769],