ARRDC4
arrestin domain containing 4
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 31615473 | WI-38, IMR-90, HUVEC, HAEC | Human | YES | |
| 31945054 | IMR-90 | Human | YES | |
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 29321003 | Primary bronchial epithelial cells derived from lung | Human | YES | |
GO terms:
Biological Process:
ubiquitin-dependent protein catabolic process [GO:0006511],
protein transport [GO:0015031],
protein ubiquitination [GO:0016567],
positive regulation of ubiquitin-protein transferase activity [GO:0051443],
Molecular Function:
protein binding, bridging involved in substrate recognition for ubiquitination [GO:1990756],
protein binding [GO:0005515],
Cellular Component:
cytoplasm [GO:0005737],
endosome [GO:0005768],
plasma membrane [GO:0005886],
membrane [GO:0016020],
cytoplasmic vesicle [GO:0031410],
intracellular membrane-bounded organelle [GO:0043231],
extracellular vesicle [GO:1903561],
early endosome [GO:0005769],