MPPE1

metallophosphoesterase 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
27323328 Saos-2,H1299, HT18, MCF7, MDA-MB-231, Li-Fraumeni Human YES
29548335 Saos-2 Human YES

GO terms:

Biological Process:
GPI anchor biosynthetic process [GO:0006506],
ER to Golgi vesicle-mediated transport [GO:0006888],
vesicle-mediated transport [GO:0016192],

Molecular Function:
protein binding [GO:0005515],
manganese ion binding [GO:0030145],
GPI anchor binding [GO:0034235],
molecular_function [GO:0003674],
phosphoric diester hydrolase activity [GO:0008081],
hydrolase activity [GO:0016787],
metal ion binding [GO:0046872],

Cellular Component:
nucleoplasm [GO:0005654],
endoplasmic reticulum-Golgi intermediate compartment [GO:0005793],
Golgi apparatus [GO:0005794],
cis-Golgi network [GO:0005801],
integral component of membrane [GO:0016021],
endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116],
endoplasmic reticulum exit site [GO:0070971],
membrane [GO:0016020],